One Minute Poster Pitches Archive

UK & Ireland Prostate Brachytherapy Conference 2024

Abstract number 2 

Comparison of pre and post implant LUTS with implant dosimetry to determine cause of increase in post implant complications 

Sara Hodkinson, Jennifer Beeby, Ben Medford
Maidstone and Tunbridge Wells NHS Trust 

Purpose: An increased number of LDR permanent seed implant brachytherapy patients have been experiencing LUTS beyond the expected levels up to 6 months post-implant. The aim of this data collection was to identify possible causes for this increase in patient issues, looking at catheterisation/re-catheterisation rates, and the interventions needed. We aimed to compare implant statistics against clinical history of patients to highlight possible trends and consistencies that we could then evaluate and implement to improve the service. 

Methods: We collated and compared implant statistics against qualitative and quantitative patient information using a database of post-implant dosimetry (including V150 and D90) and clinical history. We then compared hotter V150 and D90 doses against patients who experienced these increased LUTS to establish if this was a potential cause. We looked at pre-implant flowmetry results, and used IPSS scores where available, to build a broader picture of the patient’s urinary baseline to facilitate drawing conclusions and to provided a point of comparison for each patient. 

Results: Currently, our findings suggest that patients with increased LUTS sometimes had hotter V150s and D90s, with approximately 4% of patients between March 2022 and 2023 having catheterisation post-implant. Pre-implant Q max does not appear to be a considerable factor in this, with a majority of patients requiring re-catheterisation having qmax >20. 

Conclusion: This audit is ongoing, but findings so far suggest our audit needs to continue in order to establish other trends. Once more trends have been identified, we can aim to implement changes to the implant procedure. 

References: 

International Prostate Symptom Score Dosimetry database