One Minute Poster Pitches Archive

UK & Ireland Prostate Brachytherapy Conference 2024

Abstract number 11 

Comparative analysis of pre-operative LDR Treatment Planning based on MRI and US prostate volume studies

Inna O’Hea, Wojciech Polak, Sarah Wilby, Harry Gibbard
Portsmouth Hospitals University NHS trust 

Purpose: The primary objective of this study is to investigate the variability in prostate volume studies obtained through magnetic resonance imaging (MRI) and transrectal ultrasound examination (TRUS), specifically in the context of pre-treatment LDR brachytherapy planning and to explore the feasibility of replacing US volume studies with MRI. 

Methods: Data of 10 patients was collected retrospectively, involving measurements from both MRI and TRUS scans. Prostate volumes were calculated using the ellipsoid formulae. The study compares the two imaging techniques by assessing their impact on seed orders and implant dosimetry. Statistical analyses were performed to determine any significant differences. 

Results: ANOVA single factor test shows (p=0.612, F (test)= 0.5 < F (crit) = 3.354) that there is statistically no significant difference between clinical volumes obtained on US scanner during LDR treatment and pre-operational MRI volumes. Two sets of pre-operative treatment plans were created based on these volumes to analyse implant dosimetry, which demonstrated that the dosimetric planning criteria can be met for seeds arrangements based on pre-operative MRI volume study. 

Conclusion: MRI volume study can be used in general clinical practice for provisional LDR brachytherapy planning. Transitioning to MRI-based volume assessment is expected to enhance time efficiency and cost-effectiveness for the procedure.